Uso da cetamina S (+) como adjuvante analgésico em pequenos animais

Abstract

The care with the health of dogs and cats becomes more and more evident with the socialization of the animal with the human; quality of life and pain control are considered very important aspects, since they are family members. Therefore, veterinarians are dedicated to recognizing and treating pain in animals, since pain perception is difficult to quantify in them. Analgesia is a fundamental issue not only for quality of life, but in pre, trans and post surgery, laboratory tests and clinical routine procedures. Therefore, knowledge of the mechanism of action of drugs that help, as adjuvants, opioids in pain management is essential. Ketamine is a dissociative drug that at low doses has promising prospects in analgesia, blocking the activation of NMDA receptors (N-methyl D-Aspartate), thus inhibiting the binding with glutamate, a nerve impulse transmitter, interrupting the painful sensation and temporarily desensitized her. The objective of this work is to review the properties of the use of ketamine and its isomers in subdoses for general analgesia.