Hiperadrenocorticismo em felinos: manifestações clinicas, métodos diagnósticos e tratamento - Revisão bibliográfica

Abstract

Although uncommon in felines, hyperadrenocorticism is an important condition to understand in this species, since it presents a challenging diagnosis and treatment. The most common clinical signs are polyuria, polydipsia, polyphagia, skin atrophy, bulging abdomen, symmetrical bilateral alopecia, weight gain and muscle atrophy. These are usually the same symptoms as diabetes mellitus or skin hyperfragility, since hyperadrenocorticism can be related to these pathologies. In laboratory tests, stress leukogram, hyperglycemia, glycosuria and hypercholesterolemia are common, and there may also be an increase in ALT and ALP. In addition to laboratory tests, this disease requires a more specific diagnosis, such as low-dose dexamethasone suppression tests, adrenocorticotropic hormone stimulation or high-dose dexamethasone suppression tests, and also the cortisol-creatinine ratio. For treatment, the use of trilostane, cabergoline, radiotherapy or hypophysectomy for pituitary tumors and unilateral or bilateral adrenalectomy are indicated. The objective of this work is to carry out, through bibliographic research, a review of the pathology of hyperadrenocorticism in felines, so that we have a deeper understanding of it, since it is less common, and thus obtain knowledge about the diagnosis and more effective forms of treatment.